Should the rivaroxaban be interrupted for this surgical extraction?
Pharmacology questions in the ADC written exam test applied prescribing decisions, not rote recall of drug names. This exam-level vignette tests your ability to work through clinical details and arrive at the correct management.
Mr. Tony Gallagher, a 66-year-old man, presents for surgical extraction of an impacted lower right wisdom tooth. He had a coronary stent placed 8 months ago and takes rivaroxaban 20 mg daily plus aspirin 100 mg daily. His cardiologist advised both medications must continue. He has no allergies and takes no other medications. Should the rivaroxaban be interrupted for this surgical extraction?
- A. Switch rivaroxaban to warfarin bridging for the perioperative period
- B. Stop both rivaroxaban and aspirin for 5 days to minimise bleeding, then restart after the socket has healed
- C. Yes — stop rivaroxaban 48 hours before all dental extractions
- D. Never interrupt DOACs for any dental procedure as the thrombotic risk always outweighs bleeding risk
- E. For lower-risk invasive procedures, interruption is not required; for higher-risk procedures like this surgical extraction, consult the patient's medical practitioner about safety and timing
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Show the answer and cited explanation
According to TG, for lower-risk invasive dental procedures, interruption of DOAC therapy is not required. For higher-risk procedures (like surgical extraction), consult the medical practitioner to assess safety and timing of any interruption. TG notes evidence on benefits of stopping DOACs before dental procedures is of low certainty. TG emphasises not stopping antithrombotics without medical advice.
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