What prophylaxis must be given, and within what timeframe?
Infection control in the ADC exam tests decision-making around exposure incidents, instrument classification, and decontamination protocols. This exam-level vignette tests your ability to work through clinical details and arrive at the correct management.
Dr Mehta's dental assistant sustains a needlestick injury from a needle used on Mrs Garcia (58F), who is known to be hepatitis B positive (HBsAg positive, HBe-antigen positive). The assistant is unsure of her own HBV vaccination status. The practice must manage both the injured worker and the source patient appropriately. The dental assistant is NOT immune to hepatitis B. What prophylaxis must be given, and within what timeframe?
- A. HBIG within 7 days plus vaccination course
- B. HBIG within 48-72 hours AND start HBV vaccination within 7 days
- C. HBV vaccination only — HBIG is not indicated
- D. HBIG within 2 weeks plus oral antiviral medication
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Show the answer and cited explanation
If the staff member is NOT immune to hepatitis B: give single dose of HBIG within 48-72 hours, AND start a course of HBV immunisation within 7 days, repeated at 1-2 months, then again at 6 months. Check antibody levels 2-4 weeks after final dose. Without prophylaxis from an HBe-antigen positive source, transmission risk exceeds 30%. (ICG p.83)
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